Bloomberg

Botulinum neurotoxin type A, sold as Allergan Inc.’s Botox remedy for wrinkles, can move from its injection site to the brain, a study shows.

Scientists injected rats’ whisker muscles with botulism toxin. Tests of the rodents’ brain tissue found that botulism had been transported to the brain stems, the researchers said in the Journal of Neuroscience published April 2.

Botox is Allergan’s biggest product, with $1.21 billion in sales last year. The drug, approved in 1989, became fashionable among aging celebrities seeking to smooth facial wrinkles and is used to treat some neurological disorders. The U.S. Food and Drug Administration is investigating whether patients contracted botulism, a muscle-weakening illness, from Botox and Myobloc, a product from Solstice Neurosciences Inc…

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